DNA or Deoxyribonucleic acid is a double-stranded molecule composed of two polynucleotide chains that coil around each other to form a double helix. DNA is responsible for carrying genetic information that is important for development, growth, functioning, and reproduction.
There are different definitions of DNA synthesis like DNA replication or DNA biosynthesis, polymerase chain reaction or enzymatic DNA synthesis, or gene synthesis. Certain bifunctional alkylating agents can create cross-link or bulky adducts that produces physical barriers to inhibit DNA synthesis and this inhibition can generate single-stranded DNA breaks which can even lead to death if they are left unpaired.
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